butabarbital will lessen the level or influence of fedratinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Impact of coadministering a solid CYP3A4 inducer with fedratinib has not been studied.butabarbital will lessen the extent or impact of lumefantrine by impacting hepatic/intestinal enzyme CYP3… Read More